Carbon Monoxide

[gilster]

Links and Discussions:

[Rose]

Research to spotlight carbon monoxide benefits
http://www.york.ac.uk/admin/presspr/pre ... search.htm

Harvard and U. Pittsburgh researchers explain carbon monoxide's anti-inflammatory effects
http://cmbi.bjmu.edu.cn/news/0703/92.htm

Carbon monoxide may protect against MS symptoms
http://www.newscientist.com/article/dn1 ... ptoms.html

Carbon Monoxide Has Medical Benefits
http://www.playfuls.com/news_006021_Car ... efits.html

Carbon monoxide could fight disease
http://www.newscientist.com/channel/hea ... alth_rss20

[Rose]

The gas in cigarette smoke 'that could save a pregnancy'

"Carbon monoxide could help control a life-threatening condition in pregnant women"
"The Canadian research followed the observation that women who smoke are less likely to develop pre-eclampsia"
http://www.dailymail.co.uk/health/artic ... nancy.html

[Rose]

Carbon monoxide soothes digestive disease

"Doctors have long known that smokers rarely suffer from a common form of inflammatory bowel disease (IBD) called ulcerative colitis, but they didn't know why. A new study in the Dec. 19 issue of The Journal of Experimental Medicine might help explain this apparent resistance. Scott Plevy, M.D., and his colleagues at the University of Pittsburgh found that carbon monoxide (CO), a component of cigarette smoke, helps shut down the intestinal inflammation that causes ulcerative colitis"
http://www.dentalplans.com/articles/Car ... digestive/

[Rose]

Therapeutic Role Found For Carbon Monoxide

"In a medical case of Jekyll and Hyde, carbon monoxide -- the highly toxic gas emitted from auto exhausts and faulty heating systems -- has proven effective in treating the symptoms of pulmonary arterial hypertension (PAH), an extremely debilitating condition that typically leads to right heart failure and eventual death."
http://www.sciencedaily.com/releases/20 ... 165352.htm

[Rose]

'Surprise benefit from carbon monoxide'

"Researchers at the University Medical Centre in Groningen, the Netherlands, found that the gas appeared to ease the inflammation of lung tissues when given in low doses over a four-day period."
http://www.irishhealth.com/?level=4&id=13267

[Rose]

Therapeutic delivery of carbon monoxide

SUMMARY OF THE INVENTION

"As exemplified by the experimental data detailed below, the present inventors have found that metal carbonyl compounds can be used to deliver CO to a physiological target so as to provide physiological effect."

"Throughout this application, references to medical treatment are intended to include both human and veterinary treatment, and references to pharmaceutical compositions are accordingly intended to encompass compositions for use in human or veterinary treatment"
http://www.pharmcast.com/Patents100/Yr2 ... 051606.htm

Carbon monoxide may protect against MS symptoms
"At the end of the trial, the mice that had breathed CO showed much greater mobility than their control counterparts"
http://www.newscientist.com/article/dn1 ... ptoms.html

[Rose]

Study finds smoking wards off Parkinson's disease

"What would cause such a preventive effect is not well understood, said the report in the Archives of Neurology, but studies on test animals suggested two possibilities.

One is that carbon monoxide or other agents in tobacco smoke exert a protective effect and promote survival of brain neurons that produce dopamine, which allows muscles to move properly and is lacking in Parkinson's cases.

Cigarettes may also somehow prevent the development of toxic substances that interfere with proper neurological functioning."
http://uk.reuters.com/article/healthNew ... 3220070709

[Rose]

'Good' Carbon Monoxide May Benefit Heart Patients

"Although the gas is lethal in large doses, small amounts can reduce inflammation, widen blood vessels, increase blood flow, prevent unwanted blood clotting – and even suppress the activity of cells and macrophages ( macrophage cells are part of the human body’s natural defence system ) which attack transplanted organs. The researchers have developed innovative water-soluble molecules which, when swallowed or injected, safely release small amounts of CO inside the human body."
http://www.scientificblogging.com/news_ ... t_patients

[Rose]

Alert over herbal cigarettes

"They contain no nicotine or tobacco, but are smoked in the usual way.

However, a team from the University of Vienna has found that the "vegetable-based" cigarettes produce a level of carbon monoxide similar to that produced by tobacco cigarettes."
http://news.bbc.co.uk/1/hi/health/backg ... 272145.stm

[Rose]

Carbon Monoxide Gas Is Used by Brain Cells As a Neurotransmitter
"THE simple gas carbon monoxide is used by nerve cells to signal each other, researchers have found in a discovery that could open the way to a new understanding of how the brain operates.

The discovery follows a finding that another simple gas, nitric oxide, can also signal nerve cells. Together the two gases break all the old rules on how neurotransmitters work"
Neurobiologists have been finding neurotransmitters since the 1920's and thought they had the rules for nerve signaling in hand. Each substance was thought to be stable and specific. One nerve cell would release the transmitter and it would fit into the next cell like a key in a lock.

But gases are volatile and nonspecific, and they diffuse into any nearby cells. Transmitters were also thought to be stored in small pouches in cells that made them and released when necessary. But gases are not stored and are made only when needed. Clinical Implications

"It's a whole brand new signaling mechanism," said Dr. Charles Stevens, a neurobiologist who is a Howard Hughes Medical Institutes investigator at the Salk Institute in La Jolla, Calif.

"So far, he added, he is finding evidence that carbon monoxide might be used to cement memories in the hippocampus of the brain and that established memories might be erased when carbon monoxide is absent."

And, he says, the new findings about carbon monoxide and nitric oxide have taught neurobiologists an important lesson: "It makes you think that when people are evaluating whether a given chemical is a candidate neurotransmitter, they ought to be very careful about applying the rules of ancient days."
http://query.nytimes.com/gst/fullpage.h ... A965958260

[Rose]

"Scenarios in which low dose carbon monoxide may be tested might include lung transplantation, stroke, heart attack, severe bacterial infections or before surgery when there might be an interruption in blood flow, such as coronary artery bypass grafting, he added."

"Pinsky explained that when a cutoff of blood triggers the clotting process, the body's own clot-dissolving machinery is suppressed by a natural protein called PAI-1.

``Carbon monoxide significantly reduces the body's production of this suppressor protein, and therefore, promotes dissolution of the clot,'' he said. ``This relieves the obstruction in small blood vessels and permits blood flow to be re-established to the organ.''

The body's own production of carbon monoxide probably evolved to protect the blood flow to vital organs, and providing extra carbon monoxide by inhalation seems to give an added boost, Pinsky said"
http://www.intelihealth.com/IH/ihtIH/EM ... 17857.html

[Rose]

Carbon monoxide plays role in orchestrating digestive tract function

"Farrugia and an associate, Dr. Joseph Szurszewski, headed the study, which focused on carbon monoxide's role in orchestrating movements of muscles in the digestive system. The results were published in the prestigious journal of the National Academy of Sciences, which is based in Washington and advises the federal government on science and technology.

They showed that cells in the digestive system manufacture tiny amounts of carbon monoxide, which then regulates muscle contractions. The contractions occur with great precision to properly move food ahead through the stomach and intestines"
http://www.post-gazette.com/healthscien ... 0617p3.asp

[Rose]

Could this be the start of the Smoking Ban Heart Miracle theory?

Second World Conference on Smoking and Health - London

"But psychologist Daniel Horn, of the U.S. Public Health Service's National Clearinghouse on Smoking and Health, observed that "under certain conditions" an increase in carbon monoxide from others' cigarettes might be harmful to someone with a heart condiition."
http://tobaccodocuments.org/lor/03659161.html

"National Clearinghouse for Smoking and Health Smoking and Health
Research Efforts to date: NCSH has done no real smoking and health research for a number of years, since it paid in the 1960s for a project in California designed to show college students "immediate effects" of smoking on the respiratory system to aid in persuading them to quit.

The results were negative and NCSH has since then concentrated on designing stop-smoking propaganda materials school "good health" curricula and public opinion surveys.

Since 1972 it has worked with American Health Foundation's Ernest Wynder on a study of "Smoking Intervention Techniques," results of which they have described as encouraging but have not reported.

Objectives: NCSH has none in smoking and health research per se, merely in "control and prevention,"
http://tobaccodocuments.org/lor/03659161.html

15

The Principle of an Anti-smoking Cure and the Introduction of the Measuring of Carbon Monoxide
Rosenburg , Copenhagen
Discussion of why people smoke.
Describes use of carbon monoxide measurements to scare patients.
http://tobaccodocuments.org/lor/00622195-2212.html

[azmac]

I do not respond to your posts but they give a lot of information. I do read them so do not quit because they are not answered. I do use some of the stuff you post in arguments with other people. In short a BIG THANKS FOR THE INFORMATION.
you can delete this post after you read it.